Here we designed an activity for instructors of all levels to help identify and mitigate implicit biases.
Here we demonstrated the C. elegans mtDNA mutation uaDf5 escapes copy number regulation. This selfish genetic element (uaDf5) exploits the mitochondrial unfolded protein response to avoid mitophagy.
Here we designed a teaching laboratory exercise for young scientists to learn about their own DNA. Students extract their DNA and genotype themselves for an inversion polymorphism on the long arm of the X chromosome.
Here we tested whether elevated mtDNA copy number found in clk-1 mutants is due to loss of ubiquinone. We found that ubiquinone supplementation did not restore mtDNA copy number to wild type levels. Thus, we infer that the elevated copy number phenotype in clk-1 mutants is due to an additional role for CLK-1.